Application for PPR Technology
EditForce focuses on development and translation of molecular tools operating both on DNA and RNA, based on PPR technology. The potential would drive innovations in various biological researches and industries.
What does PPR Genome editing system provide?
For biological researches
Recent advances of sequencing technologies enable easy assess to large DNA and RNA sequence information. EditForce’s technologies will offer the DNA modification of interest by our original genome editing, and further, various RNA modification techniques: suppression, activation and changing the splicing status, and nucleotide information. The novel PPR-based RNA technology provide an innovative solution in your research. We have particularly focused on the development of advanced technologies for studying non-coding RNA.
Genome editing has been anticipated in the medical field, especially for regenerative- and gene-therapy. Several attempts have already started using TALE and CRISPR, including chimeric antigen receptor (CAR) T cell immunotherapy and the generation of disease-relevant cells using pluripotent stem cells. Moreover, our protein-based RNA manipulation tools using RNA-binding PPR can be applied to acquired diseases, which many persons may be suffering from.
Innovation in plant breeding is indispensable to meet the challenges of global food and environmental issues in this century. The genome editing technology is anticipated in such use, because the genome editing enables fast and precise modification of plants, than previous conventional breeding techniques including recombinant DNA technologies. Further, EditForce’s RNA manipulation technology can be applied in various agricultural areas, such as production of useful substance in plants, and stable F1 seed production.
The production of various materials, special proteins or chemical compounds for a wide range of applications such as biofuels and therapeutic uses has been utilized in living organisms, including bacteria, cultured cells and plants. EditForce’s technologies, editing of both DNA and RNA, enable the optimization of the genome (DNA) and the expression circuit (DNA and RNA). These DNA/RNA operation tools would open further opportunities for cell engineering in bio-production.